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Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome facilitate tRNA translocation

An 11.7-Å-resolution cryo-EM map of the yeast 80S·eEF2 complex in the presence of the antibiotic sordarin was interpreted in molecular terms, revealing large conformational changes within eEF2 and the 80S ribosome, including a rearrangement of the functionally important ribosomal intersubunit bridge...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Spahn, Christian MT, Gomez-Lorenzo, Maria G, Grassucci, Robert A, Jørgensen, Rene, Andersen, Gregers R, Beckmann, Roland, Penczek, Pawel A, Ballesta, Juan PG, Frank, Joachim
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2004
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC380967/
https://ncbi.nlm.nih.gov/pubmed/14976550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600102
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