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Structures of modified eEF2·80S ribosome complexes reveal the role of GTP hydrolysis in translocation
On the basis of kinetic data on ribosome protein synthesis, the mechanical energy for translocation of the mRNA–tRNA complex is thought to be provided by GTP hydrolysis of an elongation factor (eEF2 in eukaryotes, EF-G in bacteria). We have obtained cryo-EM reconstructions of eukaryotic ribosomes co...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1864975/ https://ncbi.nlm.nih.gov/pubmed/17446867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601677 |
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