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Novel activity of eukaryotic translocase, eEF2: dissociation of the 80S ribosome into subunits with ATP but not with GTP

Ribosomes must dissociate into subunits in order to begin protein biosynthesis. The enzymes that catalyze this fundamental process in eukaryotes remained unknown. Here, we demonstrate that eukaryotic translocase, eEF2, which catalyzes peptide elongation in the presence of GTP, dissociates yeast 80S...

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Detalhes bibliográficos
Main Authors: Demeshkina, Natalia, Hirokawa, Go, Kaji, Akira, Kaji, Hideko
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950535/
https://ncbi.nlm.nih.gov/pubmed/17586816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm468
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