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Novel activity of eukaryotic translocase, eEF2: dissociation of the 80S ribosome into subunits with ATP but not with GTP

Ribosomes must dissociate into subunits in order to begin protein biosynthesis. The enzymes that catalyze this fundamental process in eukaryotes remained unknown. Here, we demonstrate that eukaryotic translocase, eEF2, which catalyzes peptide elongation in the presence of GTP, dissociates yeast 80S...

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書目詳細資料
Main Authors: Demeshkina, Natalia, Hirokawa, Go, Kaji, Akira, Kaji, Hideko
格式: Artigo
語言:Inglês
出版: Oxford University Press 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950535/
https://ncbi.nlm.nih.gov/pubmed/17586816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm468
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