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The role of GTP in transient splitting of 70S ribosomes by RRF (ribosome recycling factor) and EF-G (elongation factor G)

Ribosome recycling factor (RRF), elongation factor G (EF-G) and GTP split 70S ribosomes into subunits. Here, we demonstrated that the splitting was transient and the exhaustion of GTP resulted in re-association of the split subunits into 70S ribosomes unless IF3 (initiation factor 3) was present. Ho...

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Autors principals: Hirokawa, Go, Iwakura, Nobuhiro, Kaji, Akira, Kaji, Hideko
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2588517/
https://ncbi.nlm.nih.gov/pubmed/18948280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn647
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