Tanshinone I Activates the Nrf2-Dependent Antioxidant Response and Protects Against As(III)-Induced Lung Inflammation In Vitro and In Vivo

Aims: The NF-E2 p45-related factor 2 (Nrf2) signaling pathway regulates the cellular antioxidant response and activation of Nrf2 has recently been shown to limit tissue damage from exposure to environmental toxicants, including As(III). In an attempt to identify improved molecular agents for systemi...

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Bibliographische Detailangaben
Hauptverfasser: Tao, Shasha, Zheng, Yi, Lau, Alexandria, Jaramillo, Melba C., Chau, Binh T., Lantz, R. Clark, Wong, Pak K., Wondrak, Georg T., Zhang, Donna D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2013
Schlagworte:
Original Research Communications
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3809600/
https://ncbi.nlm.nih.gov/pubmed/23394605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2012.5117
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