The Nrf2-inducers tanshinone I and dihydrotanshinone protect human skin cells and reconstructed human skin against solar simulated UV

Exposure to solar ultraviolet (UV) radiation is a causative factor in skin photocarcinogenesis and photoaging, and an urgent need exists for improved strategies for skin photoprotection. The redox-sensitive transcription factor Nrf2 (nuclear factor-E2-related factor 2), a master regulator of the cel...

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Bibliografische gegevens
Hoofdauteurs: Shasha Tao, Rebecca Justiniano, Donna D. Zhang, Georg T. Wondrak
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2013-01-01
Reeks:Redox Biology
Onderwerpen:
Tanshinone I
Dihydrotanshinone
Nrf2
Solar simulated ultraviolet light
Skin photoprotection
Online toegang:http://www.sciencedirect.com/science/article/pii/S2213231713000736
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