Efficient site-specific transgenesis and enhancer activity tests in medaka using PhiC31 integrase

Established transgenesis methods for fish model systems allow efficient genomic integration of transgenes. However, thus far a way of controlling copy number and integration sites has not been available, leading to variable transgene expression caused by position effects. The integration of transgen...

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Библиографические подробности
Главные авторы: Kirchmaier, Stephan, Höckendorf, Burkhard, Möller, Eva Katharina, Bornhorst, Dorothee, Spitz, Francois, Wittbrodt, Joachim
Формат: Artigo
Язык:Inglês
Опубликовано: Company of Biologists 2013
Предметы:
Techniques and Resources
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3809364/
https://ncbi.nlm.nih.gov/pubmed/24048591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.096081
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