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Site-directed zebrafish transgenesis into single landing sites with the phiC31 integrase system

BACKGROUND: Linear DNA-based and Tol2-mediated transgenesis are powerful tools for the generation of transgenic zebrafish. However, the integration of multiple copies or transgenes at random genomic locations complicates comparative transgene analysis and makes long-term transgene stability unpredic...

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Autori principali: Mosimann, Christian, Puller, Ann-Christin, Lawson, Katy L., Tschopp, Patrick, Amsterdam, Adam, Zon, Leonard I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3775328/
https://ncbi.nlm.nih.gov/pubmed/23723152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.23989
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