Bortezomib Reduces Neointimal Hyperplasia in a Rat Carotid Artery Injury Model

BACKGROUND AND OBJECTIVES: The ubiquitin-proteasome system is the major intracellular protein degradation pathway in the eukaryotic cells. Bortezomib inhibits 26S proteasome-induced I-κBα degradation and suppresses nuclear factor-kappa B (NF-κB) activation. We examined the effect of bortezomib on ne...

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Main Authors: Kim, Ki-Seok, Kim, Song Yi, Choi, Joon Hyeok, Joo, Seung Jae, Kim, Dong Woon, Cho, Myeong Chan
Format: Artigo
Language:Inglês
Published: The Korean Society of Cardiology 2013
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3808854/
https://ncbi.nlm.nih.gov/pubmed/24174959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4070/kcj.2013.43.9.592
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