Effects of Combination Therapy with Celecoxib and Doxycycline on Neointimal Hyperplasia and Inflammatory Biomarkers in Coronary Artery Disease Patients Treated with Bare Metal Stents

PURPOSE: Cyclooxygenase (COX)-2 and matrix metalloproteinase (MMP)-9 play a key role in the pathogenesis of in-stent restenosis. We investigated the effect of a short-term therapy of celecoxib, a COX-2 inhibitor, with or without doxycycline, an MMP inhibitor, after coronary stenting on inflammatory...

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Bibliographische Detailangaben
Hauptverfasser: Kim, Won Ho, Ko, Young-Guk, Kang, Ki Woon, Kim, Jung-Sun, Kim, Byung-Keuk, Choi, Donghoon, Hong, Myeong-Ki, Jang, Yangsoo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Yonsei University College of Medicine 2012
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250318/
https://ncbi.nlm.nih.gov/pubmed/22187234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3349/ymj.2012.53.1.68
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