Identification of germline genomic copy number variation in familial pancreatic cancer

Adenocarcinoma of the pancreas is a significant cause of cancer mortality, and up to 10 % of cases appear to be familial. Heritable genomic copy number variants (CNVs) can modulate gene expression and predispose to disease. Here, we identify candidate predisposition genes for familial pancreatic can...

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Main Authors: Al-Sukhni, Wigdan, Joe, Sarah, Lionel, Anath C., Zwingerman, Nora, Zogopoulos, George, Marshall, Christian R., Borgida, Ayelet, Holter, Spring, Gropper, Aaron, Moore, Sara, Bondy, Melissa, Klein, Alison P., Petersen, Gloria M., Rabe, Kari G., Schwartz, Ann G., Syngal, Sapna, Scherer, Stephen W., Gallinger, Steven
Format: Artigo
Language:Inglês
Published: 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3808836/
https://ncbi.nlm.nih.gov/pubmed/22665139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-012-1183-1
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