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Linkage Analysis of Chromosome 4 in Families with Familial Pancreatic Cancer

BACKGROUND: Approximately 10% of pancreatic ductal adenocarcinomas have a familial basis. While a small portion of this familial clustering can be explained by inherited mutations in known genes (BRCA2, p16/CDKN2A, PRSS1, and STK11), the genetic basis for the majority of this familial clustering rem...

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Auteurs principaux: Klein, Alison P., de Andrade, Mariza, Hruban, Ralph H., Bondy, Melissa, Schwartz, Ann G., Gallinger, Steven, Lynch, Henry T., Syngal, Sapna, Rabe, Kari G., Goggins, Michael G., Petersen, Gloria M.
Format: Artigo
Langue:Inglês
Publié: 2007
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3144722/
https://ncbi.nlm.nih.gov/pubmed/17312386
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