TERT promoter mutations in bladder cancer affect patient survival and disease recurrence through modification by a common polymorphism

The telomerase reverse transcriptase (TERT) promoter, an important element of telomerase expression, has emerged as a target of cancer-specific mutations. Originally described in melanoma, the mutations in TERT promoter have been shown to be common in certain other tumor types that include glioblast...

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Hlavní autoři: Rachakonda, P. Sivaramakrishna, Hosen, Ismail, de Verdier, Petra J., Fallah, Mahdi, Heidenreich, Barbara, Ryk, Charlotta, Wiklund, N. Peter, Steineck, Gunnar, Schadendorf, Dirk, Hemminki, Kari, Kumar, Rajiv
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3808633/
https://ncbi.nlm.nih.gov/pubmed/24101484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1310522110
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