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Pore waters regulate ion permeation in a calcium release-activated calcium channel
The recent crystal structure of Orai, the pore unit of a calcium release-activated calcium (CRAC) channel, is used as the starting point for molecular dynamics and free-energy calculations designed to probe this channel’s conduction properties. In free molecular dynamics simulations, cations localiz...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3808583/ https://ncbi.nlm.nih.gov/pubmed/24101457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1316969110 |
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