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Exploring conformational states of the bacterial voltage-gated sodium channel NavAb via molecular dynamics simulations

The X-ray structure of the bacterial voltage-gated sodium channel NavAb has been reported in a conformation with a closed conduction pore. Comparison between this structure and the activated-open and resting-closed structures of the voltage-gated Kv1.2 potassium channel suggests that the voltage-sen...

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Bibliografiske detaljer
Main Authors: Amaral, Cristiano, Carnevale, Vincenzo, Klein, Michael L., Treptow, Werner
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535635/
https://ncbi.nlm.nih.gov/pubmed/23150565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1218087109
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