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Exploring conformational states of the bacterial voltage-gated sodium channel NavAb via molecular dynamics simulations

The X-ray structure of the bacterial voltage-gated sodium channel NavAb has been reported in a conformation with a closed conduction pore. Comparison between this structure and the activated-open and resting-closed structures of the voltage-gated Kv1.2 potassium channel suggests that the voltage-sen...

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Hlavní autoři: Amaral, Cristiano, Carnevale, Vincenzo, Klein, Michael L., Treptow, Werner
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535635/
https://ncbi.nlm.nih.gov/pubmed/23150565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1218087109
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