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Bidirectional Crosstalk between the Estrogen Receptor and Human Epidermal Growth Factor Receptor 2 Signaling Pathways in Breast Cancer: Molecular Basis and Clinical Implications
The estrogen receptor (ER) and/or the human epidermal growth factor receptor 2 (HER2) signaling pathways are the dominant drivers of cell proliferation and survival in the majority of human breast cancers. As a result, targeting these pathways provides the most effective therapies in appropriately s...
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Main Authors: | , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
S. Karger GmbH
2013
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3808214/ https://ncbi.nlm.nih.gov/pubmed/24415978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000354253 |
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