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Bidirectional Crosstalk between the Estrogen Receptor and Human Epidermal Growth Factor Receptor 2 Signaling Pathways in Breast Cancer: Molecular Basis and Clinical Implications

The estrogen receptor (ER) and/or the human epidermal growth factor receptor 2 (HER2) signaling pathways are the dominant drivers of cell proliferation and survival in the majority of human breast cancers. As a result, targeting these pathways provides the most effective therapies in appropriately s...

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Detalhes bibliográficos
Main Authors: Giuliano, Mario, Trivedi, Meghana V., Schiff, Rachel
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger GmbH 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3808214/
https://ncbi.nlm.nih.gov/pubmed/24415978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000354253
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