Laddar...
Mitoxantrone Analogues as Ligands for a Stem–Loop Structure of Tau Pre-mRNA
A series of mitoxantrone (MTX) analogues have been designed, synthesized, and evaluated for binding to and stabilizing a stem–loop structure that serves as a splicing regulatory element in the pre-mRNA of tau, which is involved in Alzheimer’s and other neurodegenerative diseases. Several compounds s...
Sparad:
| Huvudupphovsmän: | , , , , , , |
|---|---|
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2009
|
| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3808193/ https://ncbi.nlm.nih.gov/pubmed/19839622 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm9013407 |
| Taggar: |
Lägg till en tagg
Inga taggar, Lägg till första taggen!
|