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An artificial di-iron oxo-protein with phenol oxidase activity
Here we report the de novo design and NMR structure of a four-helical bundle di-iron protein with phenol oxidase activity. The introduction of the cofactor-binding and phenol-binding sites required the incorporation of residues that were detrimental to the free energy of folding of the protein. Suff...
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| Asıl Yazarlar: | , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2009
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3808167/ https://ncbi.nlm.nih.gov/pubmed/19915535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.257 |
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