Structure of the CRISPR Interference Complex CSM Reveals Key Similarities with Cascade

The Clustered Regularly Interspaced Palindromic Repeats (CRISPR) system is an adaptive immune system in prokaryotes. Interference complexes encoded by CRISPR-associated (cas) genes utilize small RNAs for homology-directed detection and subsequent degradation of invading genetic elements, and they ha...

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Bibliographische Detailangaben
Hauptverfasser: Rouillon, Christophe, Zhou, Min, Zhang, Jing, Politis, Argyris, Beilsten-Edmands, Victoria, Cannone, Giuseppe, Graham, Shirley, Robinson, Carol V., Spagnolo, Laura, White, Malcolm F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cell Press 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807668/
https://ncbi.nlm.nih.gov/pubmed/24119402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.08.020
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