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Ataxin-3 Is a Multivalent Ligand for the Parkin Ubl Domain
[Image: see text] The ubiquitin signaling pathway consists of hundreds of enzymes that are tightly regulated for the maintenance of cell homeostasis. Parkin is an E3 ubiquitin ligase responsible for conjugating ubiquitin onto a substrate protein, which itself can be ubiquitinated. Ataxin-3 performs...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American
Chemical Society
2013
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| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3807529/ https://ncbi.nlm.nih.gov/pubmed/24063750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400780v |
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