Mice Lacking Functional STAT1 Are Highly Susceptible to Lethal Infection with Lassa Virus

Lassa fever (LF) is a potentially lethal human disease that is caused by the arenavirus Lassa virus (LASV). Annually, around 300,000 infections with up to 10,000 deaths occur in regions of Lassa fever endemicity in West Africa. Here we demonstrate that mice lacking a functional STAT1 pathway are hig...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Yun, Nadezhda E., Seregin, Alexey V., Walker, David H., Popov, Vsevolod L., Walker, Aida G., Smith, Jeanon N., Miller, Milagros, de la Torre, Juan C., Smith, Jennifer K., Borisevich, Viktoriya, Fair, Joseph N., Wauquier, Nadia, Grant, Donald S., Bockarie, Bayon, Bente, Dennis, Paessler, Slobodan
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology 2013
Θέματα:
Pathogenesis and Immunity
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807383/
https://ncbi.nlm.nih.gov/pubmed/23903830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01433-13
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