Isoform Selectivity of Adenylyl Cyclase Inhibitors: Characterization of Known and Novel Compounds

Nine membrane-bound adenylyl cyclase (AC) isoforms catalyze the production of the second messenger cyclic AMP (cAMP) in response to various stimuli. Reduction of AC activity has well documented benefits, including benefits for heart disease and pain. These roles have inspired development of isoform-...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Brand, Cameron S., Hocker, Harrison J., Gorfe, Alemayehu A., Cavasotto, Claudio N., Dessauer, Carmen W.
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Pharmacology and Experimental Therapeutics 2013
Teme:
Cellular and Molecular
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807061/
https://ncbi.nlm.nih.gov/pubmed/24006339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.113.208157
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki