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Isoform Selectivity of Adenylyl Cyclase Inhibitors: Characterization of Known and Novel Compounds
Nine membrane-bound adenylyl cyclase (AC) isoforms catalyze the production of the second messenger cyclic AMP (cAMP) in response to various stimuli. Reduction of AC activity has well documented benefits, including benefits for heart disease and pain. These roles have inspired development of isoform-...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The American Society for Pharmacology and Experimental Therapeutics
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3807061/ https://ncbi.nlm.nih.gov/pubmed/24006339 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.113.208157 |
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