Isoform Selectivity of Adenylyl Cyclase Inhibitors: Characterization of Known and Novel Compounds

Nine membrane-bound adenylyl cyclase (AC) isoforms catalyze the production of the second messenger cyclic AMP (cAMP) in response to various stimuli. Reduction of AC activity has well documented benefits, including benefits for heart disease and pain. These roles have inspired development of isoform-...

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Bibliografische gegevens
Hoofdauteurs: Brand, Cameron S., Hocker, Harrison J., Gorfe, Alemayehu A., Cavasotto, Claudio N., Dessauer, Carmen W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Pharmacology and Experimental Therapeutics 2013
Onderwerpen:
Cellular and Molecular
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807061/
https://ncbi.nlm.nih.gov/pubmed/24006339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.113.208157
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