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Inactivation of tumor-specific CD8(+) CTLs by tumor-infiltrating tolerogenic dendritic cells
Cancer immunosurveillance failure is largely attributed to the insufficient activation of tumor-specific class I major histocompatibility complex (MHC) molecule (MHC-I)-restricted CD8(+) cytotoxic T lymphocytes (CTLs). DEC-205(+) dendritic cells (DCs), having the ability to cross-present, can presen...
שמור ב:
| Main Authors: | , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Publishing Group
2013
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3806489/ https://ncbi.nlm.nih.gov/pubmed/24018532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/icb.2013.38 |
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