Estradiol promotes neural stem cell differentiation into endothelial lineage and angiogenesis in injured peripheral nerve

Neural stem cells (NSCs) differentiate into endothelial cells (ECs) and neuronal cells. Estradiol (E2) is known to exhibit proangiogenic effects on ischemic tissues via EC activation. Therefore, we hypothesized that E2 can promote the therapeutic potential of NSC transplantation for injured nerve re...

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Bibliografiske detaljer
Main Authors: Sekiguchi, Haruki, Ii, Masaaki, Jujo, Kentaro, Thorne, Tina, Ito, Aiko, Klyachko, Ekaterina, Hamada, Hiromichi, Kessler, John A., Tabata, Yasuhiko, Kawana, Masatoshi, Asahi, Michio, Hagiwara, Nobuhisa, Losordo, Douglas W.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3806485/
https://ncbi.nlm.nih.gov/pubmed/22941227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10456-012-9298-5
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