CXCR4 Antagonist AMD3100 Promotes Cardiac Functional Recovery After Ischemia-Reperfusion Injury via eNOS-Dependent Mechanism

BACKGROUND: CXC-chemokine receptor 4 (CXCR4) regulates the retention of stem/progenitor cells in the bone marrow (BM), and the CXCR4 antagonist AMD3100 improves recovery from coronary-ligation injury by mobilizing stem/progenitor cells from the BM to the peripheral blood. Thus, we investigated wheth...

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Detalhes bibliográficos
Main Authors: Jujo, Kentaro, Ii, Masaaki, Sekiguchi, Haruki, Klyachko, Ekaterina, Misener, Sol, Tanaka, Toshikazu, Tongers, Jörn, Roncalli, Jérôme, Renault, Marie-Ange, Thorne, Tina, Ito, Aiko, Clarke, Trevor, Kamide, Christine, Tsurumi, Yukio, Hagiwara, Nobuhisa, Qin, Gangjian, Asahi, Michio, Losordo, Douglas W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3560409/
https://ncbi.nlm.nih.gov/pubmed/23204107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.112.099242
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