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Detection of low frequency FGFR3 mutations in the urine of bladder cancer patients using next-generation deep sequencing

Biological fluid-based noninvasive biomarker assays for monitoring and diagnosing disease are clinically powerful. A major technical hurdle for developing these assays is the requirement of high analytical sensitivity so that biomarkers present at very low levels can be consistently detected. In the...

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Hlavní autoři: Millholland, John M, Li, Shuqiang, Fernandez, Cecilia A, Shuber, Anthony P
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3806441/
https://ncbi.nlm.nih.gov/pubmed/24199178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/RRU.S32736
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