Identification of low-frequency variants of UGT1A3 associated with bladder cancer risk by next-generation sequencing

Although genome-wide association studies (GWASs) have successfully revealed many common risk variants for bladder cancer, the heritability is still largely unexplained. We hypothesized that low-frequency variants involved in bladder cancer risk could reveal the unexplained heritability. Next-generat...

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Udgivet i:Oncogene
Main Authors: Zheng, Rui, Du, Mulong, Ge, Yuqiu, Gao, Fang, Xin, Junyi, Lv, Qiang, Qin, Chao, Zhu, Yao, Gu, Chengyuan, Wang, Mengyun, Zhu, Qiuyuan, Guo, Zheng, Ben, Shuai, Chu, Haiyan, Ye, Dingwei, Zhang, Zhengdong, Wang, Meilin
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8016664/
https://ncbi.nlm.nih.gov/pubmed/33658628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-021-01672-1
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