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Numb regulates acinar cell dedifferentiation and survival during pancreatic damage and acinar to ductal metaplasia
BACKGROUND & AIMS: Pancreatic ductal adenocarcinoma (PDA) is a leading cause of cancer-related death. Through the process of acinar to ductal metaplasia (ADM), pancreatic acinar cells give rise to pancreatic intraepithelial neoplasia (PanIN), the most common precursor of PDA. However, even when...
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| Huvudupphovsmän: | , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2013
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3805717/ https://ncbi.nlm.nih.gov/pubmed/23891977 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2013.07.027 |
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