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Microsatellite instability in hematological malignancies: Hypermutation vs. immune control—who is challenging who?

The genome of colorectal carcinomas displaying pronounced microsatellite instability codes for an extraordinarily high number of mutated proteins that elicit tumor-specific cellular immune responses. We have recently demonstrated that leukemic cells are also vulnerable to T cells specific for tumor-...

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Detalhes bibliográficos
Main Authors: Maletzki, Claudia, Stier, Saskia, Linnebacher, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3805632/
https://ncbi.nlm.nih.gov/pubmed/24167765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.25419
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