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Microsatellite instability in hematological malignancies: Hypermutation vs. immune control—who is challenging who?
The genome of colorectal carcinomas displaying pronounced microsatellite instability codes for an extraordinarily high number of mutated proteins that elicit tumor-specific cellular immune responses. We have recently demonstrated that leukemic cells are also vulnerable to T cells specific for tumor-...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Landes Bioscience
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3805632/ https://ncbi.nlm.nih.gov/pubmed/24167765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.25419 |
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