Isozyme-Specific Ligands for O-acetylserine sulfhydrylase, a Novel Antibiotic Target

The last step of cysteine biosynthesis in bacteria and plants is catalyzed by O-acetylserine sulfhydrylase. In bacteria, two isozymes, O-acetylserine sulfhydrylase-A and O-acetylserine sulfhydrylase-B, have been identified that share similar binding sites, although the respective specific functions...

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Detalhes bibliográficos
Main Authors: Spyrakis, Francesca, Singh, Ratna, Cozzini, Pietro, Campanini, Barbara, Salsi, Enea, Felici, Paolo, Raboni, Samanta, Benedetti, Paolo, Cruciani, Gabriele, Kellogg, Glen E., Cook, Paul F., Mozzarelli, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3805590/
https://ncbi.nlm.nih.gov/pubmed/24167577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077558
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