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Diterpene Cyclases and the Nature of the Isoprene Fold
The structures and mechanism of action of many terpene cyclases are known, but there are no structures of diterpene cyclases. Here, we propose structural models based on bioinformatics, site-directed mutagenesis, domain swapping, enzyme inhibition and spectroscopy that help explain the nature of dit...
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| Main Authors: | , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3805035/ https://ncbi.nlm.nih.gov/pubmed/20602361 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22751 |
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