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Structure and Mechanism of the Diterpene Cyclase ent-Copalyl Diphosphate Synthase

The structure of ent-copalyl diphosphate synthase (CPS) reveals three α-helical domains (α, β, γ), as also observed in the related diterpene cyclase taxadiene synthase. However, active sites are located at the interface of the βγ domains in CPS but exclusively in the α domain of taxadiene synthase....

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Detalhes bibliográficos
Main Authors: Köksal, Mustafa, Hu, Huayou, Coates, Robert M., Peters, Reuben J., Christianson, David W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118866/
https://ncbi.nlm.nih.gov/pubmed/21602811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.578
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