BET bromodomain inhibition suppresses T(H)17-mediated pathology

Interleukin (IL) 17–producing T helper (T(H)17) cells have been selected through evolution for their ability to control fungal and bacterial infections. It is also firmly established that their aberrant generation and activation results in autoimmune conditions. Using a characterized potent and sele...

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Bibliographic Details
Main Authors: Mele, Deanna A., Salmeron, Andres, Ghosh, Srimoyee, Huang, Hon-Ren, Bryant, Barbara M., Lora, Jose M.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2013
Subjects:
Brief Definitive Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3804955/
https://ncbi.nlm.nih.gov/pubmed/24101376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20130376
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