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BET bromodomain inhibition suppresses T(H)17-mediated pathology

Interleukin (IL) 17–producing T helper (T(H)17) cells have been selected through evolution for their ability to control fungal and bacterial infections. It is also firmly established that their aberrant generation and activation results in autoimmune conditions. Using a characterized potent and sele...

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Detalhes bibliográficos
Main Authors: Mele, Deanna A., Salmeron, Andres, Ghosh, Srimoyee, Huang, Hon-Ren, Bryant, Barbara M., Lora, Jose M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3804955/
https://ncbi.nlm.nih.gov/pubmed/24101376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20130376
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