Aging predisposes to acute inflammatory induced pathology after tumor immunotherapy

Cancer commonly occurs in the elderly and immunotherapy (IT) is being increasingly applied to this population. However, the majority of preclinical mouse tumor models assessing potential efficacy and toxicities of therapeutics use young mice. We assessed the impact of age on responses to systemic im...

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Detaylı Bibliyografya
Asıl Yazarlar: Bouchlaka, Myriam N., Sckisel, Gail D., Chen, Mingyi, Mirsoian, Annie, Zamora, Anthony E., Maverakis, Emanual, Wilkins, Danice E.C., Alderson, Kory L., Hsiao, Hui-Hua, Weiss, Jonathan M., Monjazeb, Arta M., Hesdorffer, Charles, Ferrucci, Luigi, Longo, Dan L., Blazar, Bruce R., Wiltrout, Robert H., Redelman, Doug, Taub, Dennis D., Murphy, William J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Rockefeller University Press 2013
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3804937/
https://ncbi.nlm.nih.gov/pubmed/24081947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20131219
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