Down-regulation of PLCγ2–β-catenin pathway promotes activation and expansion of myeloid-derived suppressor cells in cancer

Myeloid-derived suppressor cells (MDSCs) favor tumor promotion, mainly by suppressing antitumor T cell responses in many cancers. Although the mechanism of T cell inhibition is established, the pathways leading to MDSC accumulation in bone marrow and secondary lymphoid organs of tumor-bearing hosts...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Capietto, Aude-Hélène, Kim, Seokho, Sanford, Dominic E., Linehan, David C., Hikida, Masaki, Kumosaki, Tomohiro, Novack, Deborah V., Faccio, Roberta
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Rockefeller University Press 2013
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3804931/
https://ncbi.nlm.nih.gov/pubmed/24127488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20130281
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller