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Insulin Secretion Improves in Cystic Fibrosis Following Ivacaftor Correction of CFTR: A Small Pilot Study

OBJECTIVE: To determine whether the cystic fibrosis transmembrane conductance regulator (CFTR) is involved in human insulin secretion by assessing the metabolic impact of the new CFTR corrector, ivacaftor. METHODS: This open-label pilot study was conducted in CF patients with the G551D mutation give...

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Detalhes bibliográficos
Main Authors: Bellin, Melena D., Laguna, Theresa, Leschyshyn, Janice, Regelmann, Warren, Dunitz, Jordan, Billings, JoAnne, Moran, Antoinette
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3804832/
https://ncbi.nlm.nih.gov/pubmed/23952705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pedi.12026
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