Transcriptome-Guided Functional Analyses Reveal Novel Biological Properties and Regulatory Hierarchy of Human Embryonic Stem Cell-Derived Ventricular Cardiomyocytes Crucial for Maturation

Human (h) embryonic stem cells (ESC) represent an unlimited source of cardiomyocytes (CMs); however, these differentiated cells are immature. Thus far, gene profiling studies have been performed with non-purified or non-chamber specific CMs. Here we took a combinatorial approach of using systems bio...

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Détails bibliographiques
Auteurs principaux: Poon, Ellen, Yan, Bin, Zhang, Shaohong, Rushing, Stephanie, Keung, Wendy, Ren, Lihuan, Lieu, Deborah K., Geng, Lin, Kong, Chi-Wing, Wang, Jiaxian, Wong, Hau San, Boheler, Kenneth R., Li, Ronald A.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3804624/
https://ncbi.nlm.nih.gov/pubmed/24204964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077784
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