Distinct Roles of MicroRNA-1 and -499 in Ventricular Specification and Functional Maturation of Human Embryonic Stem Cell-Derived Cardiomyocytes

BACKGROUND: MicroRNAs (miRs) negatively regulate transcription and are important determinants of normal heart development and heart failure pathogenesis. Despite the significant knowledge gained in mouse studies, their functional roles in human (h) heart remain elusive. METHODS AND RESULTS: We hypot...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Fu, Ji-Dong, Rushing, Stephanie N., Lieu, Deborah K., Chan, Camie W., Kong, Chi-Wing, Geng, Lin, Wilson, Kitchener D., Chiamvimonvat, Nipavan, Boheler, Kenneth R., Wu, Joseph C., Keller, Gordon, Hajjar, Roger J., Li, Ronald A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2011
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3217986/
https://ncbi.nlm.nih.gov/pubmed/22110643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027417
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