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Migrating bubble during break-induced replication drives conservative DNA synthesis
The repair of chromosomal double strand breaks (DSBs) is crucial in the maintenance of genomic integrity. However, the repair of DSBs can also destabilize the genome by causing mutations and chromosomal rearrangements, the driving forces for carcinogenesis and hereditary diseases. Break induced repl...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3804423/ https://ncbi.nlm.nih.gov/pubmed/24025772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12584 |
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