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Optimizing parameters in clinical trials with a randomized start or withdrawal design
Disease-modifying (DM) trials on chronic diseases such as Alzheimer’s disease (AD) require a randomized start or withdrawal design. The analysis and optimization of such trials remain poorly understood, even for the simplest scenario in which only three repeated efficacy assessments are planned for...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3804275/ https://ncbi.nlm.nih.gov/pubmed/24159249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csda.2013.07.013 |
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