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Minimizing the Sample Sizes of Clinical Trials on Preclinical and Early Symptomatic Stage of Alzheimer Disease

BACKGROUND: Clinical trials of investigational drugs for Alzheimer disease (AD) increasingly focus on the prodromal (symptomatic) stage of the illness and now its preclinical (asymptomatic) stage. Sensitive and specific cognitive and functional endpoints are needed to track subtle cognitive and func...

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Detalhes bibliográficos
Publicado no:J Prev Alzheimers Dis
Main Authors: Luo, Jingqin, Weng, Hua, Morris, John C., Xiong, Chengjie
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6429951/
https://ncbi.nlm.nih.gov/pubmed/29616704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14283/jpad.2018.16
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