Minimizing the Sample Sizes of Clinical Trials on Preclinical and Early Symptomatic Stage of Alzheimer Disease

BACKGROUND: Clinical trials of investigational drugs for Alzheimer disease (AD) increasingly focus on the prodromal (symptomatic) stage of the illness and now its preclinical (asymptomatic) stage. Sensitive and specific cognitive and functional endpoints are needed to track subtle cognitive and func...

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Bibliographic Details
Published in:J Prev Alzheimers Dis
Main Authors: Luo, Jingqin, Weng, Hua, Morris, John C., Xiong, Chengjie
Format: Artigo
Language:Inglês
Published: 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6429951/
https://ncbi.nlm.nih.gov/pubmed/29616704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14283/jpad.2018.16
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