A carregar...
The impact of molecular manipulation in residue 114 of Human Immunodeficiency Virus Type-1 reverse transcriptase on dNTP substrate binding and viral replication
Human immunodeficiency virus type-1 (HIV-1) reverse transcriptase (RT) has a unique tight binding to dNTP substrates. Structural modeling of Ala-114 of HIV-1 RT suggests that longer side chains at this residue can reduce the space normally occupied by the sugar moiety of an incoming dNTP. Indeed, mu...
Na minha lista:
| Main Authors: | , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3804253/ https://ncbi.nlm.nih.gov/pubmed/22153297 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2011.11.004 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|