Stochastic homeostasis in human airway epithelium is achieved by neutral competition of basal cell progenitors

Lineage tracing approaches have provided new insights into the cellular mechanisms that support tissue homeostasis in mice. However, the relevance of these discoveries to human epithelial homeostasis and its alterations in disease is unknown. By developing a novel quantitative approach for the analy...

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Detalhes bibliográficos
Main Authors: Teixeira, Vitor H, Nadarajan, Parthiban, Graham, Trevor A, Pipinikas, Christodoulos P, Brown, James M, Falzon, Mary, Nye, Emma, Poulsom, Richard, Lawrence, David, Wright, Nicholas A, McDonald, Stuart, Giangreco, Adam, Simons, Benjamin D, Janes, Sam M
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2013
Assuntos:
Human Biology and Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3804062/
https://ncbi.nlm.nih.gov/pubmed/24151545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.00966
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