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Crystal structures of botulinum neurotoxin DC in complex with its protein receptors synaptotagmin I and II

Botulinum neurotoxins (BoNTs) can cause paralysis at exceptionally low concentrations and include seven serotypes (BoNT/A-G). The chimeric BoNT/DC toxin has a receptor binding domain similar to the same region in BoNT/C. However, BoNT/DC does not share protein receptor with BoNT/C. Instead, it share...

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Autors principals: Berntsson, Ronnie Per-Arne, Peng, Lisheng, Svensson, Linda Marie, Dong, Min, Stenmark, Pål
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3803103/
https://ncbi.nlm.nih.gov/pubmed/23932591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2013.06.026
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