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Roadmap for the design of drug-loaded thermoresponsive polypeptide nanoparticles
Chimeric polypeptides (CPs) that are derived from elastin-like polypeptides (ELPs) can self-assemble to form nanoparticles by site-specific covalent attachment of hydrophobic molecules to one end of the biopolymer backbone. Molecules with a distribution coefficient greater than 1.5 impart sufficient...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3801213/ https://ncbi.nlm.nih.gov/pubmed/23280697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201200899 |
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