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Smurf2 suppresses B-cell proliferation and lymphomagenesis by mediating ubiquitination and degradation of YY1

About half of patients with diffuse large B-cell lymphoma (DLBCL) do not respond to or relapse soon after the standard chemotherapy, indicating a critical need to better understand the specific pathways perturbed in DLBCL for developing effective therapeutic approaches. Mice deficient in the E3 ubiq...

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Détails bibliographiques
Auteurs principaux: Ramkumar, Charusheila, Cui, Hang, Kong, Yahui, Jones, Stephen N., Gerstein, Rachel M., Zhang, Hong
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3801104/
https://ncbi.nlm.nih.gov/pubmed/24121673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms3598
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